PHI-base : The Pathogen - Host Interaction Database

This database contains expertly curated molecular and biological information on genes proven to affect the outcome of pathogen-host interactions. Information is also given on the target sites of some anti-infective chemistries.

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Search	Gene	for
andor	Disease	for
andor	Host	for
andor	Pathogen	for
andor	Anti-Infective	for	all

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Version: 3.6 Last revision: 06/05/14

PHI-base is a National Capability funded by Biotechnology and Biological Sciences Research Council (BBSRC, UK) and is being developed and maintained by scientists at Rothamsted Research.

Allylamines
Benzimidazoles
Carboxylic acids
Dicarboximides
Hydroxyanilides
Methyoxyacrylates
Morpholines
N-phenyl carbamates
Oxathiin carboxamides
Thiophanates
Triazoles

Loss of pathogenicity
Reduced virulence
Unaffected pathogenicity
Increased virulence (Hypervirulence)
Enhanced antagonism
Wild-type mutualism
Effector (plant avirulence determinant)
Resistant to chemical
Sensitive to chemical
Susceptible to chemical
Lethal

gene disruption
+ gene mutation
+ gene mutation: characterised
+ gene deletion; complementation
+ gene deletion
+ complementation
+ complementation; other evidence
+ altered gene expression: overexpression
+ altered gene expression: overexpression; complementation
+ complementation; altered gene expression / gene regulation: silencing
gene deletion
+ altered gene expression: overexpression
+ overexpression
+ complementation
+ complementation; biochemical evidence
+ biochemical analysis
+ silencing
altered gene expression / gene regulation
+ downregulation
+ overexpression
+ silencing
+ down- and upregulation
+ complementation
biochemical analysis
+ mutation: characterised
+ mutation: characterised; complementation
functional test in host
+ direct injection
+ transient expression
mutation
+ characterised
+ characterised; complementation
complementation
sequence analysis of sensitive and resistant strains
sexual cross, sequencing of resistance conferring allele
other evidence