PHI-base : The Pathogen - Host Interaction Database

This database contains expertly curated molecular and biological information on genes proven to affect the outcome of pathogen-host interactions. Information is also given on the target sites of some anti-infective chemistries.

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Search	Gene	for
andor	Disease	for
andor	Host	for
andor	Pathogen	for
andor	Anti-Infective	for	all

andor	Phenotype	for	all

andor	Experimental evidence	for	all

Version: 3.5 Last revision: 04/11/13

PHI-base is a National Capability funded by Biotechnology and Biological Sciences Research Council (BBSRC, UK) and is being developed and maintained by scientists at Rothamsted Research.

Allylamines
Benzimidazoles
Carboxylic acids
Dicarboximides
Methyoxyacrylates
Morpholines
N-phenyl carbamates
Oxathiin carboxamides
Thiophanates
Triazoles

Loss of pathogenicity
Reduced virulence
Unaffected pathogenicity
Increased virulence (Hypervirulence)
Enhanced antagonism
Wild-type mutualism
Effector (plant avirulence determinant)
Resistant to chemical
Sensitive to chemical
Susceptible to chemical
Lethal

gene disruption
+ gene mutation
+ gene mutation: characterised
+ gene deletion; complementation
+ gene deletion
+ complementation
+ complementation; other evidence
+ altered gene expression: overexpression
+ altered gene expression: overexpression; complementation
+ complementation; altered gene expression / gene regulation: silencing
gene deletion
+ altered gene expression: overexpression
+ overexpression
+ complementation
+ complementation; biochemical evidence
+ biochemical analysis
+ silencing
altered gene expression / gene regulation
+ downregulation
+ overexpression
+ silencing
+ down- and upregulation
+ complementation
biochemical analysis
+ mutation: characterised
+ mutation: characterised; complementation
functional test in host
+ direct injection
+ transient expression
mutation
+ characterised
+ characterised; complementation
complementation
sequence analysis of sensitive and resistant strains
sexual cross, sequencing of resistance conferring allele
other evidence