This database contains expertly curated molecular and biological information on genes proven to affect the outcome of pathogen-host interactions. Information is also given on the target sites of some anti-infective chemistries.
Search About Release notes Download Disclaimer Errors & contributions Help Consortium
Current release:
Version 3.1
  • Improvements for some entries and sequence downloads
Table No. of records
Genes 966
Interactions 1217
Pathogens 98
Hosts 73
Diseases 63
References 672
Future release (about 3 releases are scheduled per year):
Version 3.2 Beta (password required)
Past releases:
Version 3.0 September 13th 2007
  • New entries
  • Information on anti-infective tagets
  • XML export
  • Selective export in FASTA format
  • DOIs for direct linkout to publications
Table No. of records
Genes 950
Interactions 1185
Pathogens 95
Hosts 69
Diseases 62
References 668
Version 2.31 January 25th 2007
  • Bugfixes for some sequence accessions
Version 2.3 December 22nd 2006
  • New entries: information for some bacterial genes now available
  • Links provided for GO and EC databases for most entries
  • Searchable GO terms and EC annotations
  • Experimental evidence codes are provided in the details page for most entries
  • Information on the effect of double gene mutants
  • Mapping list PHI-base accessions to EMBL identifiers
Table No. of records
Genes 643
Interactions 841
Pathogens 74
Hosts 64
Diseases 46
References 567
Version 2.2 June 2nd 2006
  • New entries
  • Definition and classification of phenotypes
  • Search by phenotype added to 'Advanced Serach' panel
  • Support of linkouts to UniProt database
  • Missing sequences added to downloadable FASTA files
  • Revised format of sequences
Table No. of records
Genes 485
Interactions 576
Pathogens 62
Hosts 54
Diseases 48
References 493
Version 2.1 October 3rd 2005
  • New entries
  • Updated phenotype information for some entries (pre/post penetration)
  • Links provided to PubMed for all entries
  • Information presented for each individual gene-host interaction
  • Abbreviations replaced with full text
  • Links provided for GO and EC databases for some entries
Table No. of records
Genes 427
Interactions 492
Pathogens 56
Hosts 42
Diseases 45
References 414
Version 2.0 August 22nd 2005
  • New web interface
  • Direct links to Pubmed
  • FASTA downloadable files
Table No. of records
Genes 379
Interactions 399
Pathogens 54
Hosts 39
Diseases 46
References 311
Version 1.0 May 4th 2005
  • 379 genes
  • Experimental host verified and updated for all entries
  • Links provided to PubMed for some entries
Table No. of records
Genes 379
Interactions 399
Pathogens 54
Hosts 39
Diseases 46
References 311
Version: 3.1 Last revision: 01/04/08
This site is sponsored by Rothamsted Research and The Biotechnology and Biological Sciences Research Council (BBSRC, UK) and is being developed and maintained by scientists at Rothamsted Research