This database contains expertly curated molecular and biological information on genes proven to affect the outcome of pathogen-host interactions. Information is also given on the target sites of some anti-infective chemistries.
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Current release:
Current release
Table No. of records
Genes 1065
Interactions 1335
Pathogens 97
Hosts 76
Diseases 64
References 720


Version 3.1
Table No. of records
Genes 966
Interactions 1217
Pathogens 98
Hosts 73
Diseases 63
References 672
Version 3.2 December 14th 2009
  • New entries
  • Bugfixes for some sequence accessions
Past releases:

Version 3.1 April 1st 2008
  • Improvements for some entries and sequence downloads
Version 3.0 September 13th 2007
  • New entries
  • Information on anti-infective tagets
  • XML export
  • Selective export in FASTA format
  • DOIs for direct linkout to publications
Version 2.31 January 25th 2007
  • Bugfixes for some sequence accessions
Version 2.3 December 22nd 2006
  • New entries: information for some bacterial genes now available
  • Links provided for GO and EC databases for most entries
  • Searchable GO terms and EC annotations
  • Experimental evidence codes are provided in the details page for most entries
  • Information on the effect of double gene mutants
  • Mapping list PHI-base accessions to EMBL identifiers
Version 2.2 June 2nd 2006
  • New entries
  • Definition and classification of phenotypes
  • Search by phenotype added to 'Advanced Serach' panel
  • Support of linkouts to UniProt database
  • Missing sequences added to downloadable FASTA files
  • Revised format of sequences
Version 2.1 October 3rd 2005
  • New entries
  • Updated phenotype information for some entries (pre/post penetration)
  • Links provided to PubMed for all entries
  • Information presented for each individual gene-host interaction
  • Abbreviations replaced with full text
  • Links provided for GO and EC databases for some entries
Version 2.0 August 22nd 2005
  • New web interface
  • Direct links to Pubmed
  • FASTA downloadable files
Version 1.0 May 4th 2005
  • 379 genes
  • Experimental host verified and updated for all entries
  • Links provided to PubMed for some entries
Version: 3.2 Last revision: 14/12/09
This site is sponsored by Rothamsted Research and The Biotechnology and Biological Sciences Research Council (BBSRC, UK) and is being developed and maintained by scientists at Rothamsted Research