This database contains expertly curated molecular and biological information on genes proven to affect the outcome of pathogen-host interactions. Information is also given on the target sites of some anti-infective chemistries.
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Current release:
Version 3.1
  • Improvements for some entries and sequence downloads
Table No. of records
Genes
Interactions
Pathogens
Hosts
Diseases
References
Future release (about 3 releases are scheduled per year):
Version 3.2 Beta (password required)
Past releases:
Version 3.0 September 13th 2007
  • New entries
  • Information on anti-infective tagets
  • XML export
  • Selective export in FASTA format
  • DOIs for direct linkout to publications
Table No. of records
Genes
Interactions
Pathogens
Hosts
Diseases
References
Version 2.31 January 25th 2007
  • Bugfixes for some sequence accessions
Version 2.3 December 22nd 2006
  • New entries: information for some bacterial genes now available
  • Links provided for GO and EC databases for most entries
  • Searchable GO terms and EC annotations
  • Experimental evidence codes are provided in the details page for most entries
  • Information on the effect of double gene mutants
  • Mapping list PHI-base accessions to EMBL identifiers
Table No. of records
Genes
Interactions
Pathogens
Hosts
Diseases
References
Version 2.2 June 2nd 2006
  • New entries
  • Definition and classification of phenotypes
  • Search by phenotype added to 'Advanced Serach' panel
  • Support of linkouts to UniProt database
  • Missing sequences added to downloadable FASTA files
  • Revised format of sequences
Table No. of records
Genes
Interactions
Pathogens
Hosts
Diseases
References
Version 2.1 October 3rd 2005
  • New entries
  • Updated phenotype information for some entries (pre/post penetration)
  • Links provided to PubMed for all entries
  • Information presented for each individual gene-host interaction
  • Abbreviations replaced with full text
  • Links provided for GO and EC databases for some entries
Table No. of records
Genes
Interactions
Pathogens
Hosts
Diseases
References
Version 2.0 August 22nd 2005
  • New web interface
  • Direct links to Pubmed
  • FASTA downloadable files
Table No. of records
Genes 379
Interactions 399
Pathogens 54
Hosts 39
Diseases 46
References 311
Version 1.0 May 4th 2005
  • 379 genes
  • Experimental host verified and updated for all entries
  • Links provided to PubMed for some entries
Table No. of records
Genes 379
Interactions 399
Pathogens 54
Hosts 39
Diseases 46
References 311
Version: 3.1 Last revision: 01/04/08
This site is sponsored by Rothamsted Research and The Biotechnology and Biological Sciences Research Council (BBSRC, UK) and is being developed and maintained by scientists at Rothamsted Research