This database contains expertly curated molecular and biological information on genes proven to affect the outcome of pathogen-host interactions
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The structure of PHI-base as an ER diagram:
ER Diagramm
PHI-base contains the following fields:
Column name Description

PHI-base accession

Stable accession number for each database entry to aid curation

EMBL accession

Link-out to EMBL Nucleotide Sequence Database

Gene name

Name of the fungal gene that was disrupted in the published study

Pathogen NCBI Taxonomy ID

NCBI taxonomy ID of the pathogenic fungus

Pathogen species

Systematic name of the pathogenic fungus

Disease name

Name of the disease caused by the pathogen host interaction

Monocot / Dicot plant

Number of cotyledons, if the host is a plant

Host NCBI Taxonomy ID

NCBI taxonomy ID of the host organism

Experimental host

Common name of the host organism

Function

Function of the disrupted gene

Pathway

Name of the pathway the disrupted gene is involved in

Phenotype of mutant

Pathogenicity phenotype of the fungus after gene disruption: reduced virulence (RV), non-pathogenic (NP), pathogenic (PA)

Mating defect

Yes/No If the gene disruption causes a mating defect affecting pathogenicity

Pre-penetration defect

Yes/No If the gene disruption causes a block in the disease process before penetration e.g. Formation of appressoria

Penetration defect

Yes/No If the gene disruption causes a block in the disease process at penetration

Post-penetration defect

Yes/No If the gene disruption causes a block in the disease process after penetration

Vegetative spores

Defects in asexual sporulation caused by the gene disruption e.g reduced sporulation

Sexual spores

Defects in sexual sporulation caused by the gene disruption e.g reduced sporulation

In vitro growth

Growth defects in culture caused by the gene disruption e.g. reduced growth

Spore germination

Defects in spore germination caused by the gene disruption

Essential gene

Lethal effect from gene disruption

Inducer

For cases where a particular compound is needed to induce gene expression e.g. Pectin

Host response

Details any difference in the host defence response to a fungus with a disrupted gene

Experimental evidence

The experimental method that is applied to disrupt the gene

Entered by

Name of the curator who entered the interaction to the database

Manual or text mining

Method of information retrieval

Literature ID

Accession number for the published article

Literature source

Name of library or information resource containing the publication

Full citation

Full citation of the article if no ID is available

Amino acid sequence

Amino acid sequence of the gene product

Nucleotide sequence

Nucleotide sequence of the gene

Comments

Field provided for any further free text information

Version: 2.1 Last revision: 01/10/05
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